Former prime minister Imran Khan has been diagnosed with Central Retinal Vein Occlusion (CRVO), a serious eye condition that can threaten vision and is often linked to underlying cardiovascular risk factors, doctors said.
CRVO develops when the central retinal vein, which drains blood from the retina, becomes blocked, most often by a clot. The blockage disrupts blood flow, causing retinal swelling, fluid leakage, and bleeding. Patients may experience sudden or progressive vision loss.
Senior ophthalmologists stress the need for close follow-up. Some patients develop complications weeks to months after onset, including neovascular glaucoma, sometimes referred to as “100-day glaucoma,” if abnormal blood vessels form and eye pressure rises.
“This is not only an eye issue,” a senior specialist said on condition of anonymity. “It can signal broader vascular disease, so patients require strict monitoring of overall health.”
CRVO Assessment and Treatment
Doctors evaluated Khan after he reported reduced vision in his right eye. He first underwent an examination at Adiala Jail, followed by detailed retinal imaging and optical coherence tomography. Based on the findings, physicians advised hospital-based care.
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He later received treatment at the Pakistan Institute of Medical Sciences, where specialists administered an intravitreal anti-VEGF injection, a standard therapy to reduce retinal swelling (macular oedema) and limit further vessel leakage.
“Patients often need injections at monthly intervals early in treatment,” the ophthalmologist said. “We adjust the schedule based on retinal response.”
Clinicians commonly use bevacizumab (Avastin) off-label due to its lower cost, while licensed options such as Eylea and Lucentis remain standard. Hospital officials did not disclose the specific drug used.
CRVO Broader Health Implications
CRVO in older adults frequently coincides with hypertension, diabetes, high cholesterol, heart rhythm disorders, or clotting issues. Doctors, therefore, coordinate eye care with assessments of blood pressure, glucose, lipids, and cardiovascular status.
“The retina offers a window into the body’s blood vessels,” the specialist added. “A retinal blockage raises our vigilance for heart and brain risks.”
Hospital officials said the procedure took about 20 minutes under sterile conditions with continuous monitoring. Khan remained stable throughout and was discharged with routine post-procedure instructions and follow-up advice.
The diagnosis has drawn public attention amid calls for transparency. Medical experts emphasise that timely treatment and regular monitoring improve the chance of preserving vision, while long-term outcomes depend on adherence to therapy and control of underlying risk factors.
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