A double-target DBS study involving 22 patients with rare tremor syndromes reported substantial tremor reduction 12 months after bilateral stimulation of the VIM and PSA brain regions.
The case series covered procedures performed between 2019 and 2023. The group’s mean tremor score fell from 3.70 before treatment to 0.45 after one year.
The technique uses a single electrode trajectory to reach both the ventral intermediate nucleus of the thalamus and the posterior subthalamic area. The approach to functional neurosurgeon Prof. Atilla Yılmaz.
Patients in the series included people with dystonic tremor and other rare tremor syndromes. However, the supplied text does not provide subgroup sizes or enough controlled data to establish effectiveness for all patients.
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A peer-reviewed review by Sanjay Pandey and Neelav Sarma states that tremor in dystonia is often postural or kinetic. It can also be mistaken for essential tremor, while treatment depends on the affected body region.
The review identifies medication and botulinum toxin as treatment options. It also says clinicians can consider DBS or lesion surgery when pharmacological treatment does not provide adequate control.
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More recent literature likewise describes DBS as an option for medically refractory dystonia, although outcomes vary between patients. Researchers stress the importance of patient selection, target choice and long-term programming.
OnlyDBS in Istanbul makes additional claims about surgical volumes, infection rates and percentage improvements. Those clinic-specific claims require independent verification before publication as clinical outcome facts.
